Nitto Avecia Pharma Services
Structural Chemistry

Structural Chemistry

With over 10-15 years industry experience per Structural Chemist, Avecia Pharma's strategic, systematic approach provides cost effective solutions for identification, characterization, and development of highly sensitive methodologies.

Partner with Avecia Pharma's Structural Chemistry Team

With a multidisciplinary team including biochemists, synthetic organic chemists, and analytical chemists, Avecia Pharma offers an array of approaches and techniques to characterize drug structures and analyze their purity at every step of the development process. In addition, Avecia Pharma's integrated team approach unites our structural chemists with scientists from other departments to provide a comprehensive set of capabilities and expertise that will efficiently accelerate and strengthen the process of characterizing and identifying complex chemical and protein compounds.

Avecia Pharma's structural chemistry team has expertise that goes beyond chemical characterizations to include a deep understanding of all facets of drug development that can impact the successful development and launch of a product. This includes experience analyzing different routes of administration, meeting regulatory requirements, solving packaging issues, and identifying potential problems in manufacturing. With in-depth academic history, diverse industry experience, and influential industry involvement, Avecia Pharma's structural chemists are unsurpassed.

expertise with an array of drug structures

  • Organic compounds
  • Minerals
  • Macromolecules

Industry-Leading Structural Chemistry Services

  • Extractables/leachables studies
  • Reference standard/ drug substance characterization
  • Structural elucidation of target/lead compounds
  • Structural elucidation of unknowns
  • Synthesis and purification of impurities and degradation products
  • Elemental analysis
  • Amino acid analysis
  • Peptide mapping
  • Glycan analysis
  • Enantiomeric studies
  • Full NMR data interpretation
  • Residual analysis in support of biotechnology-derived products
  • Residual Solvent Screening by GC/MS
  • Melamine analysis by GC/MS and LC/MS
  • Structural characterization of protein variants and isoforms

Leading-Edge Instrumentation

  • LC/MS/MS: Quadrupole, triple quadrupole of mass spectrometers with APCI & ESI
  • LC/MS-QTOF
  • GC/MS (EI and CI
  • ionization)
  • UPLC-MS/MS
  • GC (multiple detectors)
  • HPLC (multiple detectors)
  • LC-ICP-MS
  • ICP-MS
  • ICP-OES
  • Flame AA
  • GFAA
  • IC
  • Elemental Analyzer
  • FTIR
  • DSC/TGA
  • TOC

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